Introduction:

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Patients with cancer are given several medical treatments, one of which is chemotherapy. Chemotherapy is a therapy pharmacological in the form of administering cytotoxic drugs which is inserted into the body. The purpose of chemotherapy is expected to kill cancer cells of the patient. In addition, chemotherapy also has several side effects, because apart from killing cancer cells, chemotherapy can also kill cells healthy body. Nausea and vomiting as well decreased sleep quality is one of the of the many side effects of chemotherapy treatment (American Cancer Society) Society, 2016; Firmana, 2017; Committee Ministry of Health's National Cancer Control Program RI, 2015).

In chemotherapy patients, nausea is a effects of chemotherapy drugs. Chemotherapy can stimulate the nausea center is in the brain, namely the chemoreceptor trigger zone (CTZ) through afferent nerve fibers located in the medulla oblongata. Next, the stimulus responded to through afferent nerve fibers in the nerves vagus and simultaneously the nausea and vomiting center vomiting provides an autonomic reflex stimulus and sympathetic reflexes that accompany nausea and vomiting, which is in the form of abdominal muscle contractions and diaphragm, peristaltic movement of the intestine, pharyngeal and gastric irritation, distension duodenum (stimulates dopamine receptors and serotonin in the gastrointestinal tract). So that it can be concluded that the process above involves some neurotransmitters and chemoreceptors (Gupta et al., 2021; Smeltzer & Bare, 2017). Nausea felt by the patient chemotherapy is given as a therapeutic management pharmacological and non-pharmacological therapy. Pharmacological therapy in the form of administration of antiemetic drugs works by blocking afferent signals (serotonin) which can cause nausea and vomiting especially in the gastrointestinal organs. Patients are given pre-medication before chemotherapy drugs were administered to the cancer room center in the form of ondansetron and dexa methasone. This is in accordance with  articles that the author found (Herrstedt et al., 2022; Ryan, 2010). The patient said he still feel nauseous even though it has been given anti-nausea medication before chemotherapy drugs entered. Giving non-therapies pharmacologically, namely Benson relaxation aims to support or strengthen therapy pharmacological (prophylactic) which has been given with a focus on aspects client psychology, one of which is in the form of anxiety whose clinical manifestations are nauseous. Based on a literature review conducted by Nazari at.al (2023), the method Benson relaxation can improve the quality of life sleep, appetite, anxiety, and quality life. Therefore, the use of techniques Benson relaxation is recommended for improve health-related outcomes in cancer patients (Nazari at.al 2023).

Benson's relaxation method is wrong one of the easiest methods to learn and applied to patients. Relaxation methods Benson is performed by the patient it is recommended to sit in a comfortable position, close your eyes, relax everything muscles, starting from the feet to the face, breathe through the nose, done for 20 seconds minutes, and finally sat quietly for a few minutes, starting with your eyes closed and then with open eyes (Ibrahim, 2019). Benson's relaxation works by reducing anxiety through decreased muscle tension and expenditure cortisol, so that it can affect the heartbeat, breathing, and cardiac workload. Benson's relaxation regulates the hypothalamus as well as exert its effect by lowering stimulation of the sympathetic nervous system and stimulates the parasympathetic nervous system. Then Therefore Benson relaxation plays a positive role in improving sleep quality in patients by providing a sense of relaxation, reduce stress, and cortisol secretion (Sari et al., 2020). After applying Benson relaxation for five days with a time of 10 – 15 minutes, the results showed that the patient experienced a decline blood pressure measurement, pulse rate, and breathing frequency before and after Benson relaxation intervention was performed every the session. The patient said he felt better relax and calm until sleepy until almost fell asleep. The next day the patient said his body felt fresher after done Benson relaxation. Based on this, it can be concluded that conclusion that it happened improvement sleep quality in patients. This is in accordance with the results of research by Habibollahpour in 2019 showed an increase significant in the intervention group on sleep quality and including sleep quality subjective, sleep latency, sleep duration, and sleep efficiency, as well as daytime dysfunction increased significantly and there was significant differences between groups intervention and control in sleep quality including subjective sleep quality, sleep latency, sleep duration, and sleep efficiency habits after implementation of the intervention (Habibollahpour, 2019).

Acknowledgements

Thank you to Mr. G, the respondent of this research who was willing and gave his consent to this research. Thank you for Mam. Tutty Aprianti for her encouragement so that this research runs smoothly.